17α-Hydroxypregnenolone
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17α-Hydroxypregnenolone is a pregnane (C21) steroid that is obtained by hydroxylation of pregnenolone at the C17α position. This step is performed by the mitochondrial cytochrome P450 enzyme 17α-hydroxylase (CYP17A1) that is present in the adrenal and gonads. Peak levels are reached in humans at the end of puberty and then decline.[1] High levels are also achieved during pregnancy. It is also a known neuromodulator.
Quick Facts Pharmacokinetic data, Metabolism ...
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Metabolism | Adrenal, Gonads |
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ECHA InfoCard | 100.006.239 |
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Formula | C21H32O3 |
Molar mass | 332.484 g·mol−1 |
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Melting point | 268 °C (514 °F) |
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