Benzilylcholine mustard
Chemical compound / From Wikipedia, the free encyclopedia
Benzilylcholine mustard (N-2-chloroethyl-N-methyl 2-aminoethyl benzilate) is a modified version of acetylcholine, so named because after cyclization in solution it forms an aziridinium derivative that is structurally similar to benzilylcholine. It is well known for being an irreversible antagonist of the muscarinic acetylcholine receptor.[1] It has been used in pharmacological experiments investigating the relationship between receptor occupancy and response. It was also one of the tools in characterization of the muscarinic acetylcholine receptor.[2]
Quick Facts Names, Identifiers ...
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Preferred IUPAC name
2-[(2-Chloroethyl)methylamino]ethyl hydroxydi(phenyl)acetate | |
Other names
N-2-chloroethyl-N-methyl 2-aminoethyl benzilate, α-Hydroxy-α-phenylbenzeneacetic acid 2-[(2-chloroethyl)methylamino]ethyl ester | |
Identifiers | |
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CompTox Dashboard (EPA) |
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Properties | |
C19H22ClNO3 | |
Molar mass | 347.836 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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