Beta-adrenergic agonist
Medications that relax muscles of the airways / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Beta-receptor agonist?
Summarize this article for a 10 year old
Beta adrenergic agonists or beta agonists are medications that relax muscles of the airways, causing widening of the airways and resulting in easier breathing.[1] They are a class of sympathomimetic agents, each acting upon the beta adrenoceptors.[2] In general, pure beta-adrenergic agonists have the opposite function of beta blockers: beta-adrenoreceptor agonist ligands mimic the actions of both epinephrine- and norepinephrine- signaling, in the heart and lungs, and in smooth muscle tissue; epinephrine expresses the higher affinity. The activation of β1, β2 and β3 activates the enzyme, adenylate cyclase. This, in turn, leads to the activation of the secondary messenger cyclic adenosine monophosphate (cAMP); cAMP then activates protein kinase A (PKA) which phosphorylates target proteins, ultimately inducing smooth muscle relaxation and contraction of the cardiac tissue.[3]
Beta adrenergic receptor agonists | |
---|---|
Drug class | |
Class identifiers | |
Use | Bradycardia, Asthma, heart failure, etc. |
ATC code | R03 |
Biological target | Adrenergic receptors (β subtype) |
External links | |
MeSH | D000318 |
Legal status | |
In Wikidata |