Candocuronium iodide
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Candocuronium iodide (INN, formerly chandonium, HS-310)[1] is a aminosteroid neuromuscular-blocking drug. Its use within anesthesia for endotracheal intubation and for providing skeletal muscle relaxation during surgery or mechanical ventilation was briefly evaluated in clinical studies in India, though further development was discontinued due to attendant cardiovascular effects, primarily tachycardia that was about the same as the clinically established pancuronium bromide.[2][3][4][5] Candocuronium demonstrated a short duration in the body, but a rapid onset of action. It had little to no ganglion blocking activity, with a greater potency than pancuronium.[1]
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Other names | Chandonium iodide; HS-310 |
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Routes of administration | IV |
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Bioavailability | 100% (IV)[citation needed] |
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Formula | C26H46I2N2 |
Molar mass | 640.477 g·mol−1 |
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