Chromatin structure remodeling (RSC) complex
Member of the ATP-dependent chromatin remodeler family / From Wikipedia, the free encyclopedia
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RSC (Remodeling the Structure of Chromatin) is a member of the ATP-dependent chromatin remodeler family. The activity of the RSC complex allows for chromatin to be remodeled by altering the structure of the nucleosome.[1]
There are four subfamilies of chromatin remodelers: SWI/SNF, INO80, ISW1, and CHD.[2] The RSC complex is a 15-subunit chromatin remodeling complex initially found in Saccharomyces cerevisiae, and is homologous to the SWI/SNF complex found in humans.[1] The RSC complex has ATPase activity in the presence of DNA.[1]