Cushing reflex
Physiological nervous system response to increased intracranial pressure / From Wikipedia, the free encyclopedia
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Cushing reflex (also referred to as the vasopressor response, the Cushing effect, the Cushing reaction, the Cushing phenomenon, the Cushing response, or Cushing's Law) is a physiological nervous system response to increased intracranial pressure (ICP) that results in Cushing's triad of increased blood pressure, irregular breathing, and bradycardia.[1] It is usually seen in the terminal stages of acute head injury and may indicate imminent brain herniation. It can also be seen after the intravenous administration of epinephrine and similar drugs.[2] It was first described in detail by American neurosurgeon Harvey Cushing in 1901.[3]