Diflunisal
NSAID analgesic and anti-inflammatory drug / From Wikipedia, the free encyclopedia
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Diflunisal is a salicylic acid derivative with analgesic and anti-inflammatory activity.[2] It was developed by Merck Sharp & Dohme in 1971, as MK647, after showing promise in a research project studying more potent chemical analogs of aspirin.[3] It was first sold under the brand name Dolobid, marketed by Merck & Co., but generic versions are now widely available. It is classed as a nonsteroidal anti-inflammatory drug (NSAID) and is available in 250 mg and 500 mg tablets.
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Dolobid |
AHFS/Drugs.com | Monograph |
MedlinePlus | a684037 |
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Routes of administration | By mouth |
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Pharmacokinetic data | |
Bioavailability | 80-90% |
Protein binding | >99% |
Metabolism | Hepatic |
Elimination half-life | 8 to 12 hours |
Excretion | Renal |
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ECHA InfoCard | 100.040.925 |
Chemical and physical data | |
Formula | C13H8F2O3 |
Molar mass | 250.201 g·mol−1 |
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