File:Linear_PK_Example.png
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Summary
DescriptionLinear PK Example.png |
English: Time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours (τ). Absorption half-life 1 h, elimination half-life 12 h. Note that in steady state and in linear pharmacokinetics AUCτ=AUC∞. Steady state is reached after about 5 × 12 = 60 hours.
Deutsch: Plasmaspiegel über 96 Stunden nach oraler Verabreichung alle 24 Stunden (τ). Absorptionshalbswertzeit 1 h, Eliminationshalbswertzeit 12 h. Im Fließgleichgewicht (Steady state) gilt bei Vorliegen linearer Pharmakokinetik AUCτ=AUC∞. Der Steady state wird nach etwa 5 Halbwertszeiten (60 h) erreicht. |
Date | |
Source | Own work |
Author | Alfie↑↓© (Helmut Schütz) |
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4 April 2011
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 17:56, 4 April 2011 | 1,600 × 1,118 (22 KB) | Alfie66 | Larger font, added doses and dosage interval, average concentration in steady state. | |
03:15, 4 April 2011 | 1,600 × 1,118 (20 KB) | Alfie66 | {{Information |Description ={{en|1=Time course of drug plasma concentrations over 96 hours, following oral administrations every 24 hours. Absorption half-life 1 h, elimination half-life 12 h. Note that in steady state and in linear PK AUC<sub>tau</sub |
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