File:Type_ii_nuclear_receptor_action.png
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Summary
DescriptionType ii nuclear receptor action.png |
English: Created myself using CambridgeSoft BioDraw. Mechanism nuclear receptor action. This figure depicts the mechanism of a class II nuclear receptor (NR) which, regardless of ligand binding status is located in the nucleus bound to DNA. For the purpose of illustration, the nuclear receptor shown here is the thyroid hormone receptor (TR) heterodimerized to the RXR. In the absence of ligand, the TR is bound to corepressor protein. Ligand binding to TR causes a dissociation of corepressor and recruitment of coactivator protein which in turn recruit additional proteins such as RNA polymerase that are responsible for transcription of downstream DNA into RNA and eventually protein which results in a change in cell function. |
Date | |
Source | Own work |
Author | Boghog2 |
Other versions | Derivative works of this file: Acción de receptores nucleares II.png |
Licensing
Public domainPublic domainfalsefalse |
I, the copyright holder of this work, release this work into the public domain. This applies worldwide. In some countries this may not be legally possible; if so: I grant anyone the right to use this work for any purpose, without any conditions, unless such conditions are required by law. |
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30 November 2008
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Date/Time | Thumbnail | Dimensions | User | Comment | |
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current | 11:17, 30 November 2008 | 2,999 × 2,249 (1,015 KB) | Boghog | {{Information |Description={{en|1=Created myself using CambridgeSoft BioDraw. Mechanism nuclear receptor action. This figure depicts the mechanism of a class II nuclear receptor (NR) which, regardless of ligand binding status is located in the nucleus bo |
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