Glycopyrronium bromide
Chemical compound / From Wikipedia, the free encyclopedia
Dear Wikiwand AI, let's keep it short by simply answering these key questions:
Can you list the top facts and stats about Glycopyrronium bromide?
Summarize this article for a 10 year old
Glycopyrronium bromide is a medication of the muscarinic anticholinergic group.[7] It does not cross the blood–brain barrier and consequently has few to no central effects. It is given by mouth,[8] via intravenous injection, on the skin,[9] and via inhalation.[4][5][6] It is a synthetic quaternary ammonium compound.[2] The cation, which is the active moiety, is called glycopyrronium (INN)[10] or glycopyrrolate (USAN).
Clinical data | |
---|---|
Trade names | Robinul, Cuvposa, Seebri, others |
Other names | glycopyrrolate (USAN US) |
AHFS/Drugs.com | Monograph |
MedlinePlus | a602014 |
License data | |
Pregnancy category |
|
Routes of administration | By mouth, intravenous, inhalation, topical, injection, subcutaneous |
Drug class | Antimuscarinic agent |
ATC code | |
Legal status | |
Legal status | |
Pharmacokinetic data | |
Elimination half-life | 0.6–1.2 hours |
Excretion | 85% Kidney, unknown amount in the bile |
Identifiers | |
| |
CAS Number |
|
PubChem CID | |
IUPHAR/BPS | |
DrugBank |
|
ChemSpider | |
UNII |
|
KEGG | |
ChEBI | |
ChEMBL |
|
CompTox Dashboard (EPA) | |
ECHA InfoCard | 100.008.990 |
Chemical and physical data | |
Formula | C19H28BrNO3 |
Molar mass | 398.341 g·mol−1 |
3D model (JSmol) |
|
| |
| |
NY (what is this?) (verify) |
The most common side effects include irritability, flushing, blocked nose, reduced secretions in the airways, dry mouth, constipation, diarrhea, vomiting and inability to completely empty the bladder (urinary retention).[7]
In September 2012, glycopyrronium was approved for medical use in the European Union.[4] In June 2018, glycopyrronium was approved by the US Food and Drug Administration (FDA) to treat excessive underarm sweating, becoming the first drug developed specifically to reduce excessive sweating.[11] It is on the World Health Organization's List of Essential Medicines.[12]