Ioflupane (123I)
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Ioflupane (123I) is the international nonproprietary name (INN) of a cocaine analogue which is a neuro-imaging radiopharmaceutical drug, used in nuclear medicine for the diagnosis of Parkinson's disease and the differential diagnosis of Parkinson's disease over other disorders presenting similar symptoms. During the DaT scan procedure it is injected into a patient and viewed with a gamma camera in order to acquire SPECT images of the brain with particular respect to the striatum, a subcortical region of the basal ganglia.[7] The drug is sold under the brand name Datscan and is manufactured by GE Healthcare, formerly Amersham plc.
Quick Facts Clinical data, Trade names ...
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Trade names | Datscan, Striascan, Celsunax |
Other names | Ioflupane (FPCIT); [I-123] N-ω-fluoropropyl- 2β-carbomethoxy- 3β-(4-iodophenyl) nortropane |
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Routes of administration | Intravenous |
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Bioavailability | N/A |
Excretion | Kidney and fecal |
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Formula | C18H23FINO2 |
Molar mass | 431.290 g·mol−1 |
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