Ketipramine
Chemical compound / From Wikipedia, the free encyclopedia
Ketipramine (G-35,259), also known as ketimipramine or ketoimipramine, is a tricyclic antidepressant (TCA) that was tested in clinical trials for the treatment of depression in the 1960s but was never marketed.[1][2][3] It differs from imipramine in terms of chemical structure only by the addition of a ketone group, to the azepine ring, and is approximately equivalent in effectiveness as an antidepressant in comparison.[4]
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Routes of administration | Oral |
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Formula | C19H22N2O |
Molar mass | 294.398 g·mol−1 |
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It was one of the drugs prescribed by Roland Kuhn in a series of unethical experiments to test drugs on children without informed consent and without proper approval at the psychiatric hospital in Münsterlingen, Switzerland.[5][6][7]