Mefenamic acid
Chemical compound / From Wikipedia, the free encyclopedia
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Mefenamic acid is a member of the anthranilic acid derivatives (or fenamate) class of nonsteroidal anti-inflammatory drugs (NSAIDs), and is used to treat mild to moderate pain.[3][4]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Ponstel, Ponstan, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a681028 |
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Routes of administration | By mouth, rectal |
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Pharmacokinetic data | |
Bioavailability | 90% |
Protein binding | >90% |
Metabolism | Liver (CYP2C9) |
Elimination half-life | 2 hours |
Excretion | Kidney (52–67%), faeces (20–25%) |
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ECHA InfoCard | 100.000.467 |
Chemical and physical data | |
Formula | C15H15NO2 |
Molar mass | 241.290 g·mol−1 |
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Its name derives from its systematic name, dimethylphenylaminobenzoic acid. It was discovered and brought to market by Parke-Davis as Ponstel in the 1960s. It became generic in the 1980s and is available worldwide under many brand names such as Meftal.[5]