Mitragynine
Opioid analgesic compound / From Wikipedia, the free encyclopedia
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Mitragynine is an indole-based alkaloid and the most abundant active alkaloid in the Southeast Asian plant Mitragyna speciosa, commonly known as kratom.[4] The total alkaloid concentration in dried leaves ranges from 0.5 to 1.5%. In Thai varieties, mitragynine is the most abundant component (up to 66% of total alkaloids) while 7-hydroxymitragynine is a minor constituent (up to 2% of total alkaloid content). In Malaysian kratom varieties, mitragynine is present at lower concentration (12% of total alkaloids).[5] Such preparations are orally consumed and typically involve dried kratom leaves which are brewed into tea[4][5] or ground and placed into capsules.[5] Mitragynine consumption for medicinal and recreation purposes dates back centuries, although early use was primarily limited to Southeast Asian countries such as Indonesia and Thailand where the plant grows indigenously.[6] Recently, mitragynine use has spread throughout Europe and the Americas as both a recreational and medicinal drug.[7] While research into the effects of kratom have begun to emerge, investigations on the active compound mitragynine are less common.
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Formula | C23H30N2O4 |
Molar mass | 398.503 g·mol−1 |
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Melting point | 102–106 °C[3] |
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