Nicotinic antagonist
Drug that inhibits the action of acetylcholine at nicotinic acetylcholine receptors / From Wikipedia, the free encyclopedia
A nicotinic antagonist is a type of anticholinergic drug that inhibits the action of acetylcholine (ACh) at nicotinic acetylcholine receptors. These compounds are mainly used for peripheral muscle paralysis in surgery, the classical agent of this type being tubocurarine,[1] but some centrally acting compounds such as bupropion, mecamylamine, and 18-methoxycoronaridine block nicotinic acetylcholine receptors in the brain and have been proposed for treating nicotine addiction.[medical citation needed]
- Note: Succinylcholine is a nicotinic agonist. See neuromuscular blocking agents page for details on the mechanism of action.
- P. Taylor (1990). In Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th Ed., (A. G. Gilman et al., Eds.), pp. 166-186, New York: Pergamon Press.
- Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 149
- Media related to Nicotinic antagonists at Wikimedia Commons
- Nicotinic+antagonists at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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