Ormeloxifene
Chemical compound / From Wikipedia, the free encyclopedia
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Ormeloxifene, also known as centchroman, is one of the selective estrogen receptor modulators,[2] or SERMs, a class of medication which acts on the estrogen receptor. It is best known as a nonsteroidal oral contraceptive which is taken once per week. In India, ormeloxifene has been available as birth control since the early 1990s, and it was marketed there under the trade name Saheli,[3] currently available free-of-cost for the women in India as Chhaya (Centchroman).[4][5]
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Centron, Novex-DS, Saheli, Sevista, Chhaya |
Other names | Centchroman |
Routes of administration | By mouth |
Drug class | Selective estrogen receptor modulator |
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Pharmacokinetic data | |
Elimination half-life | 7 days |
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Chemical and physical data | |
Formula | C30H35NO3 |
Molar mass | 457.614 g·mol−1 |
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Quick Facts Background, Type ...
Ormeloxifene | |
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Background | |
Type | Antiestrogen |
First use | 1991 |
Failure rates (first year) | |
Perfect use | 2% |
Typical use | 9% |
Usage | |
Duration effect | One week |
Reversibility | Immediate |
User reminders | Taken twice weekly for first 13 weeks |
Clinic review | Annually |
Advantages and disadvantages | |
STI protection | No |
Periods | May disrupt |
Safe while breastfeeding | Yes[1] |
Weight | No proven effect |
Benefits | Non hormonal |
Risks | Delayed menstruation |
Medical notes | |
Only approved as a contraceptive in India |
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Ormeloxifene has also been licensed under the trade names Ormalin, Novex-DS, Centron, and Sevista.