Paliperidone
Antipsychotic medication / From Wikipedia, the free encyclopedia
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Paliperidone, sold under the brand name Invega among others, is an atypical antipsychotic.[14] It is mainly used to treat schizophrenia and schizoaffective disorder.[14] It is marketed by Janssen Pharmaceuticals.[4]
Quick Facts Clinical data, Trade names ...
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Trade names | Invega, Xeplion, Trevicta, others |
Other names | 9-hydroxyrisperidone; PP; PP1M; PP3M; PP6M; JNS-010; RO-92670; RO92670 |
AHFS/Drugs.com | Monograph |
MedlinePlus | a607005 |
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Routes of administration | By mouth, intramuscular |
Drug class | Atypical antipsychotic |
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Bioavailability | 28% (oral) |
Elimination half-life | 23 hours (by mouth) |
Excretion | 1% unchanged in urine 18% unchanged in feces |
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ECHA InfoCard | 100.117.604 |
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Formula | C23H27FN4O3 |
Molar mass | 426.492 g·mol−1 |
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Paliperidone was approved by the US Food and Drug Administration (FDA) for the treatment of schizophrenia in December 2006,[4] and in the European Union in June 2007.[8] Paliperidone palmitate is a long-acting injectable formulation of paliperidone palmitoyl ester.[14][15] It is on the World Health Organization's List of Essential Medicines.[16] Paliperidone is available as a generic medication.[13]