Perphenazine
Antipsychotic medication / From Wikipedia, the free encyclopedia
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Perphenazine is a typical antipsychotic drug. Chemically, it is classified as a piperazinyl phenothiazine. Originally marketed in the United States as Trilafon, it has been in clinical use for decades.
Quick Facts Clinical data, AHFS/Drugs.com ...
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AHFS/Drugs.com | Monograph |
MedlinePlus | a682165 |
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Routes of administration | Oral and IM |
Drug class | Typical antipsychotic |
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Bioavailability | 40% |
Metabolism | hepatic |
Elimination half-life | 8-12 (up to 20) hours |
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ECHA InfoCard | 100.000.346 |
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Formula | C21H26ClN3OS |
Molar mass | 403.97 g·mol−1 |
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Perphenazine is roughly ten times as potent as chlorpromazine at the dopamine-2 (D2) receptor;[3] thus perphenazine is considered a medium-potency antipsychotic.[4][5]