Pizotifen
Drug used to reduce frequency of headaches / From Wikipedia, the free encyclopedia
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Pizotifen (INN) or pizotyline (USAN), trade name Sandomigran, is a benzocycloheptene-based drug used as a medicine, primarily as a preventive to reduce the frequency of recurrent migraine headaches.[1]
Quick Facts Clinical data, Trade names ...
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Trade names | Sandomigran |
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Routes of administration | Oral |
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Bioavailability | 78% |
Protein binding | 91% |
Metabolism | Glucuronidation (main route). N-glucuronide accounts for >50% of plasma and 60–70% of urinary excreted drug |
Elimination half-life | 23 hours |
Excretion | 18% feces, 55% urine (both as metabolites) |
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ECHA InfoCard | 100.036.014 |
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Formula | C19H21NS |
Molar mass | 295.44 g·mol−1 |
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