Platelet factor 4
Protein involved in blood clotting, wound healing and inflammation / From Wikipedia, the free encyclopedia
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"PF4" redirects here. For SpaceShipTwo PF04, see 2014 Virgin Galactic crash. For USN Tacoma-class patrol frigate, see USS Sausalito (PF-4). For Philippine Navy frigate, see BRP Rajah Lakandula (PF-4). For JMSDF frigate, see JDS Momi (PF-4). For 1997 PF4, see 14967 Madrid. For 1999 PF4, see 38245 Marcospontes. For PF4 receptor, see PF4 receptor.
Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4) . This chemokine is released from alpha-granules of activated platelets during platelet aggregation, and promotes blood coagulation by moderating the effects of heparin-like molecules. Due to these roles, it is predicted to play a role in wound repair and inflammation.[5] It is usually found in a complex with proteoglycan.
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