Prilocaine
Local anesthetic of the amino amide type / From Wikipedia, the free encyclopedia
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Prilocaine (/ˈpraɪləˌkeɪn/[1]) is a local anesthetic of the amino amide type first prepared by Claes Tegner and Nils Löfgren. In its injectable form (trade name Citanest), it is often used in dentistry. It is also often combined with lidocaine as a topical preparation for dermal anesthesia (lidocaine/prilocaine or EMLA), for treatment of conditions like paresthesia. As it has low cardiac toxicity, it is commonly used for intravenous regional anaesthesia (IVRA).
Quick Facts Clinical data, Trade names ...
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Trade names | Citanest |
AHFS/Drugs.com | Monograph |
MedlinePlus | a603026 |
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Routes of administration | Subcutaneous |
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Protein binding | 55% |
Metabolism | Liver and kidney |
Elimination half-life | 10-150 minutes, longer with impaired liver or kidney function |
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ECHA InfoCard | 100.010.871 |
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Formula | C13H20N2O |
Molar mass | 220.316 g·mol−1 |
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Chirality | Racemic mixture |
Melting point | 37 to 38 °C (99 to 100 °F) |
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