Raphe nuclei
Moderate-size cluster of nuclei found in brain stem / From Wikipedia, the free encyclopedia
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The raphe nuclei (Greek: ῥαφή, "seam")[1] are a moderate-size cluster of nuclei found in the brain stem. They have 5-HT1 receptors which are coupled with Gi/Go-protein-inhibiting adenyl cyclase. They function as autoreceptors in the brain and decrease the release of serotonin. The anxiolytic drug Buspirone acts as partial agonist against these receptors.[2] Selective serotonin reuptake inhibitor (SSRI) antidepressants are believed to act in these nuclei, as well as at their targets.[3]
Quick Facts Details, Identifiers ...
Raphe nuclei | |
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Details | |
Identifiers | |
Latin | nuclei raphe |
MeSH | D011903 |
NeuroLex ID | nlx_anat_20090205 |
TA98 | A14.1.04.257 A14.1.04.318 A14.1.05.402 A14.1.05.601 A14.1.06.401 |
TA2 | 6035, 5955 |
FMA | 84017 |
Anatomical terms of neuroanatomy |
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