Sulfanilamide
Chemical compound / From Wikipedia, the free encyclopedia
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Sulfanilamide (also spelled sulphanilamide) is a sulfonamide antibacterial drug. Chemically, it is an organic compound consisting of an aniline derivatized with a sulfonamide group.[1] Powdered sulfanilamide was used by the Allies in World War II to reduce infection rates and contributed to a dramatic reduction in mortality rates compared to previous wars.[2][3] Sulfanilamide is rarely if ever used systemically due to toxicity and because more effective sulfonamides are available for this purpose. Modern antibiotics have supplanted sulfanilamide on the battlefield; however, sulfanilamide remains in use today in the form of topical preparations, primarily for treatment of vaginal yeast infections such as vulvovaginitis caused by Candida albicans.[4][5][6][7]
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AHFS/Drugs.com | salonemide Consumer Drug Information |
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ECHA InfoCard | 100.000.513 |
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Formula | C6H8N2O2S |
Molar mass | 172.20 g·mol−1 |
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Density | 1.08 g/cm3 |
Melting point | 165 °C (329 °F) |
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The term "sulfanilamides" is also sometimes used to describe a family of molecules containing these functional groups. Examples include: