Talk:Tricyclic antidepressant
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These drugs are not heterocyclic compounds, as the first sentence of the article suggests. See page on heterocycles
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71.192.117.165 (talk) 05:38, 19 January 2012 (UTC)
My understanding was that it was an early MAOI, which was being used to treat tuberculosis, that was found to make patients euphoric. Anyone have a source? RoseParks
I think you might be right. Deleted the reference.
Iproniazid was the drug you're thinking of, and yes, it apparently has modest MAOI activity. I wonder if perhaps by "euphoric" (if that was indeed the word used) they meant merely that the patients seemed unusually happy (which would be curious enough, given that TB was a really horrible disease). I found this in my rather old (9th ed.) copy of Goodman & Gilman. Zeller et al. were credited with first recognizing the inhibition of MAO by iproniazid, a finding later confirmed by others. (Iproniazid has since been replaced for tx of TB with the less hepatotoxic isoniazid, BTW.) Mia229 (talk) 06:56, 29 October 2013 (UTC)
What does the word "quinidineline" (referenced in the article as a type of side effect) mean? I've tried googling for it and the word yielded about 130 matches, most of which want to give me "free" ringtones and poker games. I'm at a loss. --65.114.61.232 21:01, 27 June 2006 (UTC)
This is the first type of drug mentioned in the article Appetite enhancers yet the appetite enhancing properties are given as a side effect in this article with less than a sentence devoted to them. No criticism intended, just a reader who was interested in seeing more on a specific topic 81.146.65.109 23:01, 2 January 2007 (UTC)
What does the word "quinidineline" (referenced in the article as a type of side effect) mean? I've tried googling for it and the word yielded about 130 matches, most of which want to give me "free" ringtones and poker games. I'm at a loss. --65.114.61.232 21:01, 27 June 2006 (UTC)
I am a pharmacy tech student and I looked up quinidineline in the mosby's drug consult it is another drug that can be used and has the same effects as the tricyclic antidepressant to which you were looking at. If that is any help...(24.230.39.40 00:09, 11 February 2007 (UTC))
Perhaps a reference to the risk of induction of mania would be useful. Dixon pete 22:13, 10 May 2007 (UTC)