Triprolidine
Antihistamine medication / From Wikipedia, the free encyclopedia
Triprolidine is an over-the-counter antihistamine with anticholinergic properties.[1] It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms.[2] As with many antihistamines, the most common side effect is drowsiness.[1]
This article is about the drug. For the Roman province, see Tripolitania. For the city, see Tripoli.
Quick Facts Clinical data, Trade names ...
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Trade names | Flonase Nighttime Allergy Relief, Actidil, Myidil, Actifed (in the latter combined with pseudoephedrine and either dextromethorphan or guaifenesin) |
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Routes of administration | Oral |
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Bioavailability | 4% oral |
Protein binding | 90% |
Metabolism | Hepatic (CYP2D6) |
Elimination half-life | 4–6 hours |
Excretion | Renal |
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ECHA InfoCard | 100.006.934 |
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Formula | C19H22N2 |
Molar mass | 278.399 g·mol−1 |
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Melting point | 60 °C (140 °F) |
Solubility in water | 500 mg/mL (20 °C) |
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It was patented in 1948 and came into medical use in 1953.[3]