Type 1 regulatory T cell
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Type 1 regulatory cells or Tr1 (TR1) cells are a class of regulatory T cells participating in peripheral immunity as a subsets of CD4+ T cells. Tr1 cells regulate tolerance towards antigens of any origin. Tr1 cells are self or non-self antigen specific and their key role is to induce and maintain peripheral tolerance[1] and suppress tissue inflammation in autoimmunity and graft vs. host disease.[2]
This article provides insufficient context for those unfamiliar with the subject. (April 2018) |