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From Wikipedia, the free encyclopedia
Abirritants, also known as anti-itch drugs are medications used for relieving or preventing itching (pruritus) around the body.[1]
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Common indications for abirritants include dermatitis, eczema, psoriasis, allergic reactions, itch caused by chronic kidney disease and related conditions.[2]
Abirritants consist of a large group of drugs belonging to different classes with varying mechanisms to treat itch. They may work either directly or indirectly to relieve itch, and evidence on their effectiveness varies from one class to another.[3] Some alternative medicines are also used to treat itch.[4][5] Side effects of abirritants also vary depending on the class of the drug. Even before the emergence of modern evidence-based medicine, abirritants have already been used in many civilizations, but practices and choice of drugs may differ by culture.[6]