User:ZoRachel/sandbox
From Wikipedia, the free encyclopedia
Gut Specific Homing is the mechanism in which activated T cells and Antibody-secreting cells (ASCs) are to both inflamed and non-inflamed regions of the gut in order to provide an effective immune response. This process relies on the key interaction between the integrin α4β7 and the addressin MadCAM-1 on the surfaces of the appropriate cells. Additionally, this interaction is strengthened by the presence of CCR9,a chemokine receptor, which interacts with TECK. The Vitamin A-derived Retinoic Acid level regulates the expression of the cell surface proteins.