Template:PBB/3479维基媒体模板 / 維基百科,自由的 encyclopedia 速览 Insulin-like growth factor 1 (somatomedin C) 胰岛素样生长因子1(生长调节素C), 有效结构 ...Insulin-like growth factor 1 (somatomedin C)胰岛素样生长因子1(生长调节素C) PDB rendering based on 1bqt. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1B9G, 1BQT, 1GF1, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSP, 2DSQ, 2DSR, 2GF1, 3GF1, 3LRI 标识代号 IGF1; IGF-I; IGF1A; IGFI扩展标识 遗传学:147440 鼠基因:96432 同源基因:515 GeneCards: IGF1 Gene 基因本体论描述 分子功能 · insulin receptor binding · insulin-like growth factor receptor binding · integrin binding · hormone activity · protein binding · growth factor activity 细胞成分 · extracellular region · extracellular space · plasma membrane · insulin-like growth factor binding protein complex · platelet alpha granule lumen 生物过程 · skeletal system development · cell activation · blood vessel remodeling · platelet degranulation · DNA replication · cellular component movement · signal transduction · Ras protein signal transduction · muscle organ development · blood coagulation · positive regulation of cell proliferation · negative regulation of cell proliferation · glycolate metabolic process · glial cell differentiation · positive regulation of cardiac muscle hypertrophy · positive regulation of phosphatidylinositol 3-kinase signaling · skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration · muscle hypertrophy · myotube cell development · positive regulation of smooth muscle cell migration · positive regulation of cerebellar granule cell precursor proliferation · water homeostasis · proteoglycan biosynthetic process · platelet activation · mammary gland development · exocrine pancreas development · regulation of establishment or maintenance of cell polarity · positive regulation of protein import into nucleus, translocation · negative regulation of smooth muscle cell apoptotic process · multicellular organism growth · bone mineralization involved in bone maturation · regulation of multicellular organism growth · positive regulation of activated T cell proliferation · positive regulation of tyrosine phosphorylation of Stat5 protein · positive regulation of DNA binding · positive regulation of MAPK cascade · positive regulation of insulin-like growth factor receptor signaling pathway · cellular protein metabolic process · myoblast differentiation · positive regulation of osteoblast differentiation · positive regulation of glycogen biosynthetic process · positive regulation of DNA replication · positive regulation of glycolytic process · positive regulation of mitosis · positive regulation of transcription, DNA-templated · positive regulation of transcription from RNA polymerase II promoter · positive regulation of glucose import · positive regulation of Ras protein signal transduction · insulin-like growth factor receptor signaling pathway · phosphatidylinositol-mediated signaling · positive regulation of fibroblast proliferation · lung alveolus development · positive regulation of smooth muscle cell proliferation · branching morphogenesis of an epithelial tube · inner ear development · chondroitin sulfate proteoglycan biosynthetic process · positive regulation of epithelial cell proliferation · positive regulation of peptidyl-tyrosine phosphorylation · myoblast proliferation · positive regulation of protein kinase B signaling · lung vasculature development · lung lobe morphogenesis · Type I pneumocyte differentiation · Type II pneumocyte differentiation · prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis · prostate gland growth · prostate gland stromal morphogenesis · negative regulation of androgen receptor signaling pathway · negative regulation of ERK1 and ERK2 cascade · positive regulation of calcineurin-NFAT signaling cascade · negative regulation of release of cytochrome c from mitochondria · extrinsic apoptotic signaling pathway in absence of ligand · positive regulation of myoblast proliferation · negative regulation of extrinsic apoptotic signaling pathway Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 3479 16000Ensembl ENSG00000017427 ENSMUSG00000020053UniProt P05019 P05017mRNA序列 NM_000618 NM_001111274蛋白序列 NP_000609 NP_001104744基因位置 Chr 12:102.79 – 102.87 Mb Chr 10:87.86 – 87.94 MbPubMed查询 [1] [2]查论编关闭
速览 Insulin-like growth factor 1 (somatomedin C) 胰岛素样生长因子1(生长调节素C), 有效结构 ...Insulin-like growth factor 1 (somatomedin C)胰岛素样生长因子1(生长调节素C) PDB rendering based on 1bqt. 有效结构 PDB 直系同源检索:PDBe, RCSB PDB查询代码列表 1B9G, 1BQT, 1GF1, 1GZR, 1GZY, 1GZZ, 1H02, 1H59, 1IMX, 1PMX, 1TGR, 1WQJ, 2DSP, 2DSQ, 2DSR, 2GF1, 3GF1, 3LRI 标识代号 IGF1; IGF-I; IGF1A; IGFI扩展标识 遗传学:147440 鼠基因:96432 同源基因:515 GeneCards: IGF1 Gene 基因本体论描述 分子功能 · insulin receptor binding · insulin-like growth factor receptor binding · integrin binding · hormone activity · protein binding · growth factor activity 细胞成分 · extracellular region · extracellular space · plasma membrane · insulin-like growth factor binding protein complex · platelet alpha granule lumen 生物过程 · skeletal system development · cell activation · blood vessel remodeling · platelet degranulation · DNA replication · cellular component movement · signal transduction · Ras protein signal transduction · muscle organ development · blood coagulation · positive regulation of cell proliferation · negative regulation of cell proliferation · glycolate metabolic process · glial cell differentiation · positive regulation of cardiac muscle hypertrophy · positive regulation of phosphatidylinositol 3-kinase signaling · skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration · muscle hypertrophy · myotube cell development · positive regulation of smooth muscle cell migration · positive regulation of cerebellar granule cell precursor proliferation · water homeostasis · proteoglycan biosynthetic process · platelet activation · mammary gland development · exocrine pancreas development · regulation of establishment or maintenance of cell polarity · positive regulation of protein import into nucleus, translocation · negative regulation of smooth muscle cell apoptotic process · multicellular organism growth · bone mineralization involved in bone maturation · regulation of multicellular organism growth · positive regulation of activated T cell proliferation · positive regulation of tyrosine phosphorylation of Stat5 protein · positive regulation of DNA binding · positive regulation of MAPK cascade · positive regulation of insulin-like growth factor receptor signaling pathway · cellular protein metabolic process · myoblast differentiation · positive regulation of osteoblast differentiation · positive regulation of glycogen biosynthetic process · positive regulation of DNA replication · positive regulation of glycolytic process · positive regulation of mitosis · positive regulation of transcription, DNA-templated · positive regulation of transcription from RNA polymerase II promoter · positive regulation of glucose import · positive regulation of Ras protein signal transduction · insulin-like growth factor receptor signaling pathway · phosphatidylinositol-mediated signaling · positive regulation of fibroblast proliferation · lung alveolus development · positive regulation of smooth muscle cell proliferation · branching morphogenesis of an epithelial tube · inner ear development · chondroitin sulfate proteoglycan biosynthetic process · positive regulation of epithelial cell proliferation · positive regulation of peptidyl-tyrosine phosphorylation · myoblast proliferation · positive regulation of protein kinase B signaling · lung vasculature development · lung lobe morphogenesis · Type I pneumocyte differentiation · Type II pneumocyte differentiation · prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis · prostate gland growth · prostate gland stromal morphogenesis · negative regulation of androgen receptor signaling pathway · negative regulation of ERK1 and ERK2 cascade · positive regulation of calcineurin-NFAT signaling cascade · negative regulation of release of cytochrome c from mitochondria · extrinsic apoptotic signaling pathway in absence of ligand · positive regulation of myoblast proliferation · negative regulation of extrinsic apoptotic signaling pathway Sources: Amigo / QuickGO RNA表达模式 更多表达数据直系同源体物种 人类 小鼠Entrez 3479 16000Ensembl ENSG00000017427 ENSMUSG00000020053UniProt P05019 P05017mRNA序列 NM_000618 NM_001111274蛋白序列 NP_000609 NP_001104744基因位置 Chr 12:102.79 – 102.87 Mb Chr 10:87.86 – 87.94 MbPubMed查询 [1] [2]查论编关闭