Glucagon rescue
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Glucagon rescue is the emergency injection of glucagon in case of severe diabetic hypoglycemia. It is needed during seizures and/or unconsciousness by an insulin user who is unable at that point to help themselves. Glucagon will facilitate the release of stored glucose back into the bloodstream, raising the blood glucose level.
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Rescue has been simplified by the development of the glucagon hypoglycemia rescue kit, consisting of:
- biosynthetic human glucagon, in a freeze dried form within a vial,
- a sturdy syringe, pre-filled with a sterile diluting solution, and
- a conspicuous red or orange colored plastic storage box, which includes instructions.
At the first signs of hypoglycemia, an insulin user should treat it immediately by consuming carbohydrate to restore blood glucose to safe levels (thereby preventing progression to severe hypoglycemia). However, not all insulin users can feel and recognize the early signs, particularly when sleeping. This can quickly lead to an emergency resulting in unconsciousness, inability to swallow, seizures, and in extreme cases death. In the past, treatment consisted of intravenous delivery of dextrose (glucose) usually in a hospital emergency department; however, the delay in treatment due to emergency response and transport to a medical facility is life-threatening.
The glucagon rescue kit facilitates rapid rescue by a simple injection, which does not require medical expertise, and can be done quickly and easily outside of a medical facility.[1][2][3]