EZH2From Wikipedia, the free encyclopedia EGFR-antisens RNK 1 je protein koji je kod ljudi kodiran genom EGFR-AS1.[5] Kratke činjenice Dostupne strukture, PDB ...EZH2Dostupne strukturePDBPretraga ortologa: PDBe RCSB Spisak PDB ID kodova4MI0, 4MI5, 5HYN, 5IJ8, 5IJ7IdentifikatoriAliasiEZH2Vanjski ID-jeviOMIM: 601573 MGI: 107940 HomoloGene: 37926 GeneCards: EZH2 Lokacija gena (čovjek)Hrom.Hromosom 7 (čovjek)[1]Bend7q36.1Početak148,807,257 bp[1]Kraj148,884,321 bp[1]Lokacija gena (miš)Hrom.Hromosom 6 (miš)[2]Bend6 B2.3|6 22.92 cMPočetak47,530,139 bp[2]Kraj47,595,341 bp[2]Obrazac RNK ekspresijeViše referentnih podataka o ekspresijiOntologija genaMolekularna funkcija• GO:0102674, GO:0102675 methyltransferase activity• sequence-specific DNA binding• aktivnost sa transferazom• promoter-specific chromatin binding• chromatin binding• histone-lysine N-methyltransferase activity• protein-lysine N-methyltransferase activity• GO:0001948, GO:0016582 vezivanje za proteine• vezivanje sa RNK• ribonucleoprotein complex binding• chromatin DNA binding• RNA polymerase II core promoter sequence-specific DNA binding• primary miRNA binding• vezivanje sa DNK• histone methyltransferase activity• histone methyltransferase activity (H3-K27 specific)• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific• GO:0001106 transcription corepressor activityĆelijska komponenta• ESC/E(Z) complex• pronucleus• jedro• nukleoplazma• citoplazma• TelomeraBiološki proces• regulation of protein phosphorylation• regulation of gliogenesis• response to estradiol• GO:0009373 regulation of transcription, DNA-templated• positive regulation of MAP kinase activity• rhythmic process• negative regulation of retinoic acid receptor signaling pathway• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II• negative regulation of striated muscle cell differentiation• G1 to G0 transition• GO:1901227 negative regulation of transcription by RNA polymerase II• positive regulation of dendrite development• positive regulation of epithelial to mesenchymal transition• negative regulation of transcription elongation from RNA polymerase II promoter• transcription, DNA-templated• negative regulation of DNA-binding transcription factor activity• positive regulation of protein serine/threonine kinase activity• negative regulation of gene expression• GO:1990376 negative regulation of G1/S transition of mitotic cell cycle• histone H3-K27 methylation• GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity• Metilacija DNK• negative regulation of epidermal cell differentiation• Metilacija• negative regulation of gene expression, epigenetic• regulation of cell population proliferation• regulation of circadian rhythm• skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration• cerebellar cortex development• Regulacija ekspresije gena• GO:0045996 negative regulation of transcription, DNA-templated• protein localization to chromatin• hippocampus development• regulation of neurogenesis• cellular response to hydrogen peroxide• response to tetrachloromethane• cellular response to trichostatin A• histone H3-K27 trimethylation• cardiac muscle hypertrophy in response to stress• hepatocyte homeostasis• liver regeneration• Metilacija histona• negative regulation of G0 to G1 transition• GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization• positive regulation of cell population proliferation• positive regulation of cell cycle G1/S phase transitionIzvori:Amigo / QuickGOOrtoloziVrsteČovjekMišEntrez214614056EnsemblENSG00000106462ENSMUSG00000029687UniProtQ15910Q61188RefSeq (mRNK)NM_001203247NM_001203248NM_001203249NM_004456NM_152998NM_001146689NM_007971RefSeq (bjelančevina)NP_001190176NP_001190177NP_001190178NP_004447NP_694543NP_001140161NP_031997Lokacija (UCSC)Chr 7: 148.81 – 148.88 MbChr 6: 47.53 – 47.6 MbPubMed pretraga[3][4]WikipodaciPogledaj/uredi – čovjekPogledaj/uredi – mišZatvori
EGFR-antisens RNK 1 je protein koji je kod ljudi kodiran genom EGFR-AS1.[5] Kratke činjenice Dostupne strukture, PDB ...EZH2Dostupne strukturePDBPretraga ortologa: PDBe RCSB Spisak PDB ID kodova4MI0, 4MI5, 5HYN, 5IJ8, 5IJ7IdentifikatoriAliasiEZH2Vanjski ID-jeviOMIM: 601573 MGI: 107940 HomoloGene: 37926 GeneCards: EZH2 Lokacija gena (čovjek)Hrom.Hromosom 7 (čovjek)[1]Bend7q36.1Početak148,807,257 bp[1]Kraj148,884,321 bp[1]Lokacija gena (miš)Hrom.Hromosom 6 (miš)[2]Bend6 B2.3|6 22.92 cMPočetak47,530,139 bp[2]Kraj47,595,341 bp[2]Obrazac RNK ekspresijeViše referentnih podataka o ekspresijiOntologija genaMolekularna funkcija• GO:0102674, GO:0102675 methyltransferase activity• sequence-specific DNA binding• aktivnost sa transferazom• promoter-specific chromatin binding• chromatin binding• histone-lysine N-methyltransferase activity• protein-lysine N-methyltransferase activity• GO:0001948, GO:0016582 vezivanje za proteine• vezivanje sa RNK• ribonucleoprotein complex binding• chromatin DNA binding• RNA polymerase II core promoter sequence-specific DNA binding• primary miRNA binding• vezivanje sa DNK• histone methyltransferase activity• histone methyltransferase activity (H3-K27 specific)• GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding• GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific• GO:0001106 transcription corepressor activityĆelijska komponenta• ESC/E(Z) complex• pronucleus• jedro• nukleoplazma• citoplazma• TelomeraBiološki proces• regulation of protein phosphorylation• regulation of gliogenesis• response to estradiol• GO:0009373 regulation of transcription, DNA-templated• positive regulation of MAP kinase activity• rhythmic process• negative regulation of retinoic acid receptor signaling pathway• GO:0044324, GO:0003256, GO:1901213, GO:0046019, GO:0046020, GO:1900094, GO:0061216, GO:0060994, GO:1902064, GO:0003258, GO:0072212 regulation of transcription by RNA polymerase II• negative regulation of striated muscle cell differentiation• G1 to G0 transition• GO:1901227 negative regulation of transcription by RNA polymerase II• positive regulation of dendrite development• positive regulation of epithelial to mesenchymal transition• negative regulation of transcription elongation from RNA polymerase II promoter• transcription, DNA-templated• negative regulation of DNA-binding transcription factor activity• positive regulation of protein serine/threonine kinase activity• negative regulation of gene expression• GO:1990376 negative regulation of G1/S transition of mitotic cell cycle• histone H3-K27 methylation• GO:0032320, GO:0032321, GO:0032855, GO:0043089, GO:0032854 positive regulation of GTPase activity• Metilacija DNK• negative regulation of epidermal cell differentiation• Metilacija• negative regulation of gene expression, epigenetic• regulation of cell population proliferation• regulation of circadian rhythm• skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration• cerebellar cortex development• Regulacija ekspresije gena• GO:0045996 negative regulation of transcription, DNA-templated• protein localization to chromatin• hippocampus development• regulation of neurogenesis• cellular response to hydrogen peroxide• response to tetrachloromethane• cellular response to trichostatin A• histone H3-K27 trimethylation• cardiac muscle hypertrophy in response to stress• hepatocyte homeostasis• liver regeneration• Metilacija histona• negative regulation of G0 to G1 transition• GO:0031497, GO:0006336, GO:0034724, GO:0001301, GO:0007580, GO:0034652, GO:0010847 chromatin organization• positive regulation of cell population proliferation• positive regulation of cell cycle G1/S phase transitionIzvori:Amigo / QuickGOOrtoloziVrsteČovjekMišEntrez214614056EnsemblENSG00000106462ENSMUSG00000029687UniProtQ15910Q61188RefSeq (mRNK)NM_001203247NM_001203248NM_001203249NM_004456NM_152998NM_001146689NM_007971RefSeq (bjelančevina)NP_001190176NP_001190177NP_001190178NP_004447NP_694543NP_001140161NP_031997Lokacija (UCSC)Chr 7: 148.81 – 148.88 MbChr 6: 47.53 – 47.6 MbPubMed pretraga[3][4]WikipodaciPogledaj/uredi – čovjekPogledaj/uredi – mišZatvori