Afamelanotide
Chemical compound / From Wikipedia, the free encyclopedia
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Afamelanotide, sold under the brand name Scenesse, is a medication used to prevent phototoxicity and to reduce pain from light exposure for people with erythropoietic protoporphyria.[1][2][4] It is a melanocortin 1 receptor (MC1-R) agonist[1] and a synthetic peptide and analogue of α-melanocyte stimulating hormone.[1] It is administered as subcutaneous implant.[3]
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Quick Facts Clinical data, Pronunciation ...
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Pronunciation | /ˌæfəmɛˈlænoʊtaɪd/ ⓘ |
Trade names | Scenesse |
Other names | [Nle4,D-Phe7]α-MSH; NDP-α-MSH; NDP-MSH; Melanotan; Melanotan-1; Melanotan I; EPT1647; CUV1647; |
AHFS/Drugs.com | Monograph |
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Routes of administration | Subcutaneous |
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Elimination half-life | 30 minutes[3] |
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Formula | C78H111N21O19 |
Molar mass | 1646.874 g·mol−1 |
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The US Food and Drug Administration (FDA) considers it to be a first-in-class medication.[5]