BD1067
Chemical compound / From Wikipedia, the free encyclopedia
BD1067 or N-[2-(3,4-dichlorophenyl)ethyl]-N-ethyl-1-pyrrolidineethanamine is a selective sigma receptor antagonist, with a reported binding affinity of Ki = 2 ± 0.5 nM for the sigma-1 receptor and greater than 19 times selectivity over the sigma-2 receptor.[1]
Quick Facts Identifiers, CAS Number ...
Identifiers | |
---|---|
| |
CAS Number | |
PubChem CID | |
ChemSpider | |
UNII | |
Chemical and physical data | |
Formula | C16H24Cl2N2 |
Molar mass | 315.28 g·mol−1 |
3D model (JSmol) | |
| |
|
Close
Like other sigma receptor antagonists, pretreating Swiss Webster mice with BD1067 significantly attenuates the behavioral toxicity of cocaine.[1]