Cilazapril
Antihypertensive drug of the ACE inhibitor class / From Wikipedia, the free encyclopedia
Cilazapril is an angiotensin-converting enzyme inhibitor (ACE inhibitor) used for the treatment of hypertension and congestive heart failure.[1][2]
Quick Facts Names, Identifiers ...
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Preferred IUPAC name
(1S,9S)-9-{[(2S)-1-Ethoxy-1-oxo-4-phenylbutan-2-yl]amino}-10-oxooctahydro-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid | |
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ChEBI | |
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ECHA InfoCard | 100.168.764 |
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Properties | |
C22H31N3O5 | |
Molar mass | 417.506 g·mol−1 |
log P | 2.212 |
Acidity (pKa) | 2.285 |
Basicity (pKb) | 11.712 |
Pharmacology | |
C09AA08 (WHO) | |
Oral | |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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It was patented in 1982 and approved for medical use in 1990.[3]