Cucurmosin
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Cucurmosin is a type I ribosome inactivating protein (RIP) found in the sarcocarp (flesh) and seed of Cucurbita — notably Cucurbita moschata, that is toxic to cancer cells,[1] if the dosage is high enough, by stopping their ribosomes.[2] Cucurmosin is what Cucurbita use to defend against viral, fungal, and bacterial agents. It takes a lower dose of cucurmosin to kill cancer cells than healthy cells.[3] It has been shown to induce apoptosis in pancreatic cancer and myeloid leukemia cells.[4]