Hachimoji DNA
Synthetic DNA / From Wikipedia, the free encyclopedia
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Hachimoji DNA (from Japanese 八文字 hachimoji, "eight letters") is a synthetic nucleic acid analog that uses four synthetic nucleotides in addition to the four present in the natural nucleic acids, DNA and RNA. This leads to four allowed base pairs: two unnatural base pairs formed by the synthetic nucleobases in addition to the two normal pairs. Hachimoji bases have been demonstrated in both DNA and RNA analogs, using deoxyribose and ribose respectively as the backbone sugar.[1][2][3][4][5]
Benefits of such a nucleic acid system may include an enhanced ability to store data, as well as insights into what may be possible in the search for extraterrestrial life.[5][6]
The hachimoji DNA system produced one type of catalytic RNA (ribozyme or aptamer) in vitro.