Homeobox protein MSX-1
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Homeobox protein MSX-1, is a protein that in humans is encoded by the MSX1 gene.[5][6] MSX1 transcripts are not only found in thyrotrope-derived TSH cells, but also in the TtT97 thyrotropic tumor, which is a well differentiated hyperplastic tissue that produces both TSHß- and a-subunits and is responsive to thyroid hormone. MSX1 is also expressed in highly differentiated pituitary cells which until recently was thought to be expressed exclusively during embryogenesis.[7] There is a highly conserved structural organization of the members of the MSX family of genes and their abundant expression at sites of inductive cell–cell interactions in the embryo suggest that they have a pivotal role during early development.[8]