Icatibant
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Icatibant, sold under the brand name Firazyr, is a medication for the symptomatic treatment of acute attacks of hereditary angioedema (HAE) in adults with C1-esterase-inhibitor deficiency.[4][2][3] It is not effective in angioedema caused by medication from the ACE inhibitor class.[5]
Quick Facts Clinical data, Trade names ...
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Trade names | Firazyr |
Other names | Hoe 140, JE 049[1] |
AHFS/Drugs.com | Monograph |
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Routes of administration | Subcutaneous |
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Formula | C59H89N19O13S |
Molar mass | 1304.54 g·mol−1 |
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It is a peptidomimetic consisting of ten amino acids, which is a selective and specific antagonist of bradykinin B2 receptors.