KCNK3
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Potassium channel subfamily K member 3 is a protein that in humans is encoded by the KCNK3 gene.[5][6][7][8]
Quick Facts Available structures, PDB ...
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Aliases | KCNK3, K2p3.1, OAT1, PPH4, TASK, TASK-1, TBAK1, potassium two pore domain channel subfamily K member 3, TASK1 | ||||||||||||||||||||||||||||||||||||||||||||||||||
External IDs | OMIM: 603220 MGI: 1100509 HomoloGene: 1692 GeneCards: KCNK3 | ||||||||||||||||||||||||||||||||||||||||||||||||||
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This gene encodes K2P3.1, one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. K2P3.1 is an outwardly rectifying channel that is sensitive to changes in extracellular pH and is inhibited by extracellular acidification. Also referred to as an acid-sensitive potassium channel, it is activated by the anesthetics halothane and isoflurane. Although three transcripts are detected in northern blots, there is currently no sequence available to confirm transcript variants for this gene.[8]