MBD1
Protein-coding gene in the species Homo sapiens / From Wikipedia, the free encyclopedia
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Methyl-CpG-binding domain protein 1 is a protein that in humans is encoded by the MBD1 gene.[5][6][7] The protein encoded by MBD1 binds to methylated sequences in DNA, and thereby influences transcription. It binds to a variety of methylated sequences, and appears to mediate repression of gene expression. It has been shown to play a role in chromatin modification through interaction with the histone H3K9 methyltransferase SETDB1. H3K9me3 is a repressive modification.
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