MOCS3 - Wikiwand
For faster navigation, this Iframe is preloading the Wikiwand page for MOCS3.

MOCS3

From Wikipedia, the free encyclopedia

MOCS3
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMOCS3, UBA4, molybdenum cofactor synthesis 3
External IDsOMIM: 609277 MGI: 1916622 HomoloGene: 6108 GeneCards: MOCS3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_014484

NM_001160330

RefSeq (protein)

NP_055299

NP_001153802

Location (UCSC)Chr 20: 50.96 – 50.96 Mbn/a
PubMed search[2][3]
Wikidata
View/Edit HumanView/Edit Mouse

Adenylyltransferase and sulfurtransferase MOCS3 is an enzyme that in humans is encoded by the MOCS3 gene.[4][5]

Molybdenum cofactor (MoCo) is necessary for the function of all molybdoenzymes. One of the enzymes required for the biosynthesis of MoCo is molybdopterin synthase (MPT synthase). The protein encoded by this gene adenylates and activates MPT synthase. This gene contains no introns. A pseudogene of this gene is present on chromosome 14.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000124217 - Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ Matthies A, Nimtz M, Leimkuhler S (May 2005). "Molybdenum cofactor biosynthesis in humans: identification of a persulfide group in the rhodanese-like domain of MOCS3 by mass spectrometry". Biochemistry. 44 (21): 7912–20. doi:10.1021/bi0503448. PMID 15910006.
  5. ^ a b "Entrez Gene: MOCS3 molybdenum cofactor synthesis 3".

Further reading


{{bottomLinkPreText}} {{bottomLinkText}}
MOCS3
Listen to this article