Mepivacaine
Local anaesthetic / From Wikipedia, the free encyclopedia
Mepivacaine /mɛˈpɪvəkeɪn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (less rapid than that of procaine) and medium duration of action (longer than that of procaine)[2][3] and is marketed under various trade names including Carbocaine and Polocaine.
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AHFS/Drugs.com | Consumer Drug Information |
MedlinePlus | a603026 |
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ECHA InfoCard | 100.002.313 |
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Formula | C15H22N2O |
Molar mass | 246.354 g·mol−1 |
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Mepivacaine became available in the United States in the 1960s.
Mepivacaine is used in any infiltration and local anesthesia.
It is supplied as the hydrochloride salt of the racemate,[4] which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties.[4]
Mepivacaine was originally synthesized in Sweden at the laboratory of Bofors Nobelkrut in 1956.[5]