Meprobamate
Carbamate derivative used as an anxiolytic drug / From Wikipedia, the free encyclopedia
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"Miltown" redirects here. For places with the name Milltown, see Milltown (disambiguation).
Meprobamate—marketed as Miltown by Wallace Laboratories and Equanil by Wyeth, among others—is a carbamate derivative used as an anxiolytic drug. It was the best-selling minor tranquilizer for a time, but has largely been replaced by the benzodiazepines due to their wider therapeutic index (lower risk of toxicity at therapeutically prescribed doses) and lower incidence of serious side effects.
Quick Facts Clinical data, Trade names ...
Clinical data | |
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Trade names | Miltown, Equanil, Meprospan, Amepromat, Quivet, Zirponand, and many others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a682077 |
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Routes of administration | Oral |
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Pharmacokinetic data | |
Bioavailability | ? |
Metabolism | Hepatic |
Elimination half-life | 10 hours |
Excretion | Renal |
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ECHA InfoCard | 100.000.306 |
Chemical and physical data | |
Formula | C9H18N2O4 |
Molar mass | 218.253 g·mol−1 |
3D model (JSmol) | |
Density | 1.229 g/cm3 |
Melting point | 105 to 106 °C (221 to 223 °F) |
Boiling point | 200 °C (392 °F) to 210 °C (410 °F) |
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