Methyl fluoroacetate
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Methyl fluoroacetate (MFA) is an organic compound with the chemical formula FCH2CO2CH3. It is an extremely toxic methyl ester of fluoroacetic acid. It is a colorless, odorless liquid at room temperature. It is used as a laboratory chemical and as a rodenticide. Because of its extreme toxicity, MFA was studied for potential use as a chemical weapon.[1]
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
Methyl fluoroacetate | |
Other names
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Identifiers | |
3D model (JSmol) |
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ChemSpider | |
ECHA InfoCard | 100.006.563 |
EC Number |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
FCH2CO2CH3 | |
Molar mass | 92.069 g·mol−1 |
Appearance | Colorless liquid |
Odor | Odorless or faint fruity |
Melting point | −40 °C (−40 °F; 233 K) |
Boiling point | 104 °C (219 °F; 377 K) |
117 g/L at 25 °C | |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards |
Extremely toxic |
GHS labelling: | |
Danger | |
H226, H300, H315, H319, H335, H400 | |
P210, P233, P240, P241, P242, P243, P261, P264, P270, P271, P273, P280, P301+P310, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P370+P378, P391, P403+P233, P403+P235, P405, P501 | |
Flash point | −32 °C (−26 °F; 241 K) |
Lethal dose or concentration (LD, LC): | |
LD50 (median dose) |
6 mg/kg (mice) |
Related compounds | |
Related compounds |
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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The general population is not likely to be exposed to methyl fluoroacetate. People who use MFA for work, however, can breathe in or have direct skin contact with the substance.[2]