Morphinan
Chemical compound / From Wikipedia, the free encyclopedia
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Not to be confused with 3-Methoxymorphinan.
Morphinan is the prototype chemical structure of a large chemical class of psychoactive drugs, consisting of opiate analgesics, cough suppressants, and dissociative hallucinogens, among others. Typical examples include compounds such as morphine, codeine, and dextromethorphan (DXM). Despite related molecular structures, the pharmacological profiles and mechanisms of action between the various types of morphinan substances can vary substantially. They tend to function either as μ-opioid receptor agonists (analgesics), or NMDA receptor antagonists (dissociatives).
Quick Facts Names, Identifiers ...
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IUPAC name
Morphinan[1] | |
Systematic IUPAC name
(4aR,10R,10aR)-1,3,4,9,10,10a-Hexahydro-2H-10,4a-(azanoethano)phenanthrene | |
Identifiers | |
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3D model (JSmol) |
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1375527 | |
ChEBI | |
ChemSpider |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C16H21N | |
Molar mass | 227.351 g·mol−1 |
Density | 1.58 g/cm3 |
Boiling point | 115±0.05 °C (liquid oil) |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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