N-Ethylmaleimide
Organic compound derived from maleic acid / From Wikipedia, the free encyclopedia
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N-Ethylmaleimide (NEM) is an organic compound that is derived from maleic acid. It contains the amide functional group, but more importantly it is an alkene that is reactive toward thiols and is commonly used to modify cysteine residues in proteins and peptides.[2]
Quick Facts Names, Identifiers ...
Names | |
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Preferred IUPAC name
1-Ethyl-1H-pyrrole-2,5-dione | |
Other names
Ethylmaleimide | |
Identifiers | |
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3D model (JSmol) |
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Abbreviations | NEM |
112448 | |
ChEBI | |
ChEMBL | |
ChemSpider |
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DrugBank |
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ECHA InfoCard | 100.004.449 |
EC Number |
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405614 | |
KEGG |
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PubChem CID |
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UNII | |
CompTox Dashboard (EPA) |
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Properties | |
C6H7NO2 | |
Molar mass | 125.12528 |
Melting point | 43 to 46 °C (109 to 115 °F; 316 to 319 K) |
Boiling point | 210 °C (410 °F; 483 K) |
Hazards | |
GHS labelling: | |
Danger | |
H300, H301, H311, H314, H317 | |
P260, P261, P264, P270, P272, P280, P301+P310, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P322, P330, P333+P313, P361, P363, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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