Naringenin
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Not to be confused with naringin.
Naringenin is a flavanone from the flavonoid group of polyphenols. It is commonly found in a variety of citrus fruits and is the predominant flavonone in grapefruit.[2] Naringenin has demonstrated numerous biological activities, including anti-inflammatory properties, antioxidant activity and skin healing.[3][4][5][6] It is used as a cosmetic ingredient and dietary supplement.[7] Naringenin (along with furanocoumarins presented in citrus fruits) is thought to be responsible for CYP3A4 suppression in the intestinal wall, that may result in serious changes of pharmacokinetics in drugs related with this enzyme.[8][9][10]
Quick Facts Names, Identifiers ...
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IUPAC name
(2S)-4′,5,7-Trihydroxyflavan-4-one | |
Systematic IUPAC name
(2S)-5,7-Dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one | |
Other names
Naringetol; Salipurol; Salipurpol | |
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ECHA InfoCard | 100.006.865 |
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Properties | |
C15H12O5 | |
Molar mass | 272.256 g·mol−1 |
Melting point | 251 °C (484 °F; 524 K)[1] |
475 mg/L[citation needed] | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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