Nimesulide
Anti-inflammatory drug / From Wikipedia, the free encyclopedia
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Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) with pain medication and fever reducing properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis, and primary dysmenorrhoea in adolescents and adults above 12 years old.
Quick Facts Clinical data, AHFS/Drugs.com ...
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Routes of administration | By mouth, rectal, topical |
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Protein binding | >97.5% |
Metabolism | Hepatic |
Elimination half-life | 1.8–4.7h |
Excretion | Renal (50%), fecal (29%) |
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ECHA InfoCard | 100.052.194 |
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Formula | C13H12N2O5S |
Molar mass | 308.31 g·mol−1 |
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Side effects may include liver problems.[1] It has a multifactorial mode of action and is characterized by a fast onset of action. It works by blocking the production of prostaglandins (a chemical associated with pain), thereby relieving pain and inflammation.