Nuciferine
Chemical compound / From Wikipedia, the free encyclopedia
Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera.[1][2]
Names | |
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IUPAC name
1,2-Dimethoxy-6aβ-aporphine | |
Systematic IUPAC name
(6aR)-1,2-Dimethoxy-6-methyl-5,6,6a,7-tetrahydro-4H-dibenzo[de,g]quinoline | |
Other names
(R)-1,2-Dimethoxyaporphine | |
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Properties | |
C19H21NO2 | |
Molar mass | 295.376 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Preliminary psychopharmacological research in 1978 was unable to conclusively determine the compound's classification regarding dopamine-receptor activity.[3] On one hand, investigative studies found evidence of behavior traditionally associated with dopamine-receptor stimulation: stereotypy, increase in spontaneous motor activity, inhibition of conditioned avoidance response, and an increase in pain sensitivity resulting in an inhibition of morphine analgesia.[3] On the other hand, these early investigative studies also found evidence of behavior traditionally associated with dopamine-receptor blockade: decrease of spontaneous motor activity, chills, catalepsy, trance-like states of consciousness.[3]