Oxaprozin
Chemical compound / From Wikipedia, the free encyclopedia
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Oxaprozin, also known as oxaprozinum, is a nonsteroidal anti-inflammatory drug (NSAID),[2] used to relieve the inflammation, swelling, stiffness, and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically, it is a propionic acid derivative. Safety and efficacy has been established in children over 6 years with juvenile rheumatoid arthritis only, and there is an increased risk of adverse reactions in the elderly population.
Quick Facts Clinical data, Trade names ...
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Trade names | Daypro, Dayrun, Duraprox, others |
AHFS/Drugs.com | Monograph |
MedlinePlus | a693002 |
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Routes of administration | By mouth |
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Bioavailability | 95% |
Protein binding | 99% |
Metabolism | Liver—65% oxidation and 35% glucuronic acid conjugation. 5% are active phenolic metabolites. |
Elimination half-life | 54.9 hours |
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ECHA InfoCard | 100.040.254 |
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Formula | C18H15NO3 |
Molar mass | 293.322 g·mol−1 |
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It was patented in 1967 and approved for medical use in 1983.[3]